In a backdoor pilot episode from The Danny Thomas Show, Andy mentions to Opie that his mother passed away when Opie was “the least little speck of a baby.” Though the character’s death was briefly discussed on the series, the story never went any further. Regardless of whether or not Opie’s Maw passed away during his early childhood, the absence of a wife allowed Andy to develop his iconic father-son relationship with Opie and refocus the narrative on the values that defined the show.
Throughout the series, Andy Taylor had a number of love interests, including Nurse Peggy and Ellie May. However, Helen Crump was the only one to become his long-term girlfriend and eventual wife. She first appeared in the second season of The Andy Griffith Show and would go on to appear in 249 episodes of the series and its spinoff, Mayberry RFD.
Though Helen and Andy eventually got married, the couple wasn’t seen or mentioned again until the 1986 made-for-TV reunion movie Return to Mayberry. When the film explained that Andy had retired from his job as a postal inspector in Cleveland, he returned to Mayberry to seek the office of sheriff once more. The film also explained that Helen had moved away, leaving Opie to raise himself.
Despite the fact that Opie didn’t have any maternal relatives seen on the series, Andy did have paternal aunts and uncles in Mayberry, such as Barney, Aunt Bee, and Bradford Taylor. The omission of a maternal figure in the life of the fictional family was likely a result of budget constraints and time limitations, as it would be impossible for the cast to keep up with multiple sets and multiple locations.